Hair Loss Shampoo: a Topical DHT Blocker for Your Hair

HIGH INTENSITY HEALTH – Let’s discuss more about topical Ketoconazole as a tool that may slow hair loss.


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The Science Behind Ketoconazole Shampoo and Hair Loss

If you’re here, you’ve probably heard that ketoconazole shampoo (generic Nizoral®) , the medicated shampoo that fights itch and dandruff, could also be beneficial for guys with male pattern hair loss.

While ketoconazole isn’t FDA-approved to treat hair loss and doesn’t block DHT, scientific evidence is mounting that it might be an effective treatment option. And when it comes to a chronic condition like male pattern baldness, it makes sense to look into anything that might be able to help you—especially if experts are the one’s saying it might work (unlike that juice cleanse your uncle won’t stop recommending).

That’s why we’re digging into the science behind using ketoconazole for hair loss. Read on to get to the bottom of whether or not this shampoo really can help you hang onto your hair.

What is ketoconazole shampoo usually used for?

Ketoconazole is an antifungal medication that’s typically used to treat stuff like athlete’s foot and ringworm. When added to shampoo, it helps fight the fungus that causes flakes and itching. (Spoiler alert: That same fungus can also accelerate hair loss.)

Can ketoconazole treat hair loss?

That’s still an open question. The FDA hasn’t approved ketoconazole shampoo for hair loss treatment, but that hasn’t stopped doctors from prescribing it that way for years. In fact, even hair loss expert and Keeps Medical Advisor Dr. Antonella Tosti backs it.

“I recommend ketoconazole shampoo to many of my patients who have androgenic alopecia, even if they don’t have dandruff,” Dr. Tosti says. “The data shows that it can help regrow hair and fight the inflammation that is associated with androgenic alopecia.”

Speaking of data…

What does the clinical evidence say?

The data isn’t fully conclusive, but there is a long record of evidence that ketoconazole can help slow down hair loss and maybe even boost growth.

Back in 1998, a study published in the scientific journal Dermatology found that 2% ketoconazole shampoo increased hair density, as well as the proportion and size of hair follicles. In fact, it’s nearly as effective as the FDA-approved topical treatment minoxidil.

In 2004, researchers discovered a potential explanation for ketoconazole’s follicle-boosting effect: It reduces inflammation known to contribute to male pattern hair loss. That study also found that ketoconazole was more effective when combined with another FDA-approved hair loss treatment, finasteride.

Since then, scientists have kept uncovering more evidence that ketoconazole can effectively treat hair loss, either alone or in addition to a proven treatment option. This review of the medical literature can fill you in if you’re interested in the details.

How does it work?

Remember the fungus that causes dandruff we mentioned earlier? It’s called Malassezia, and it’s found on every human head. But when it builds up too much, it causes inflammation, which in turn causes flakes, itching, and maybe even increased hair loss.

Studies have found that men with male pattern baldness have more Malassezia on their heads than other people. By killing excess Malassezia, ketoconazole soothes the inflammation that’s at the root of dandruff, itch, and hair loss.

That’s why other hair loss shampoos can’t keep their promises: Without ketoconazole, they can’t reduce inflammation, and inflammation is what accelerates hair loss.

How can I get it?

You can get 1% ketoconazole shampoo over the counter, but you’ll need to speak to a doctor to get the 2% version. The percentage refers to the concentration of ketoconazole in the shampoo, which is why you need a prescription for the stronger 2% version.

While ketoconazole shampoo hasn’t been approved by the FDA for hair loss treatment just yet, the record of scientific evidence that shows that it can help is promising. Hair loss experts haven’t waited around for the FDA to give them permission to use an effective treatment, and many already consider ketoconazole a standard part of any treatment plan.


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This $11 ‘Miracle Shampoo’ Stops Dandruff, Itchiness, and Hair Loss

Over 39,000 shoppers love the formula.


Dandruff isn’t glamorous, but it is persistent—so much so that when little white snowflakes and scalp itchiness are affecting your day to day life, it can feel like anything would be worth it to find a cure. As someone with seborrheic dermatitis, I’ve been down that road, and can tell you that the glowing reviews for Nizoral’s $15 dandruff shampoo are right on the money.

Unlike other dandruff shampoos that rely on pyrithione zinc, Nizoral’s formula uses 1 percent ketoconazole.

Per the brand, it’s the only over-the-counter dandruff shampoo to do so—which might be why it’s Amazon’s best-selling shampoo, and a top-seller in Amazon’s overall beauty category (and with over 20,000 hair care products alone on Amazon, that’s no slight praise).

Yet, the spotlight makes sense for the midnight blue bottle.

Over 39,000 shoppers have decreed the formula worth a five-star rating, and over 5,000 have added their two cents on why it’s so good. The highlights: It clears up dander incredibly quickly, cleans hair, adds a nice shine, and aids hair growth as a pleasant side effect.

“This stuff is absolutely amazing. I had severe dandruff that was so bad, I could shake my head and it would come off,” writes one person, who says they were one step away from heading to the dermatologist. “With just a few uses per week, I got rid of all of my flakes. My scalp also stopped burning from dryness. My hair has never been healthier.”

Another reviewer says: “Changed my life!!! It is the only thing that actually gets rid of the itching, scaling, and buildup. I suggest this to everyone I know who has dandruff. The plus is that it is also just a really good shampoo, [and] leaves your hair very clean and soft.” Clean and soft isn’t the end of it, with more people emphasizing how “shiny and smooth” it leaves their strands.

The shampoo’s so hardworking that it cracks the case even for someone who experiences chronic scalp dermatitis and PCOS—and it reversed the “dramatic” thinning the twofer created. “I’m SO excited. I bought this shampoo as a last resort, after trying Head and Shoulders, charcoal shampoos, biotin shampoos and scalp clarifying solutions,” the reviewer wrote. “My scalp was noticeably clearer after two uses, so I kept using it about two to three times a week. After almost a month, I realized I have new hair growth all over my scalp!”

According to research published in the journal Biomedical Dermatology, the hair growth effects aren’t placebo; while it doesn’t work quite as quickly as remedies like minoxidil, ketoconazole does encourage hair growth. Not a bad consequence of clearing up dandruff, I’d say. Especially when the positives don’t stop there: Shoppers with peeling skin, dermatitis, and acne on their face say it’s a godsend, too.

“It virtually fixed all of my problems within three days, and I didn’t feel any discomfort or itching,” writes one person.

“All of my peeling skin, on both my scalp and face, quite literally just rolled off in my fingertips, revealing the smooth, baby-soft skin beneath. It’s been life changing. You can buy it at Walgreens for about $30, so I recommend an Amazon subscription instead. Took me years to get to this point. Just try it, it might work for you.”

A last fan says: “MIRACLE shampoo!!! I’ve had scales and flakes since my daughter was born. I noticed immediate results, as in, no flakes and no itching after ONE use!!! I’ve been using this shampoo, as directed, with each shower and I have not had a single reoccurrence. My psoriasis is GONE, and like Fräulein Maria, I will shout it to the hills and back again.”



Hey fellas, today I’m going to share a secret about avoiding hair loss. Male pattern baldness, caused by Dihydrotestosterone DHT, is not problematic.

It’s what helps you build muscles.

DHT is significant, but it can accelerate male pattern baldness. If you have a familiar or genetic predisposition to losing hair, I’ll let you know about something I’ve been using for quite some time. I’m not being paid by these people whatsoever. I want to be honest with you about the stuff I use. I’ve talked about DHEA. I’ve talked to you about vitamin D, electrolytes, and increasing everything. I use this three days a week when I’m washing my hair. Now I’m big on avoiding perfumes and chemicals. Unfortunately, this stuff does have EDTA, sodium lauryl sulfate, and a bunch of chemicals. It’s got a fragrance in there, but this is the worst thing I possibly put on my body. It’s only a few days per week, and this is because Ketoconazole helps to neutralize or prevent DHT from damaging the hair.

You can use 2 percent Ketoconazole shampoo to treat thinning hair.

It is double the potency of regular shampoo but is available at any Pharmacist.

If you are on hormone replacement therapy or taking steroids, you should get off those as they will accelerate your hair loss. You can take Ketoconazole shampoo and rub it in the spots where you lose hair. For most men, it will be right around here or the back of the crown. Let it sit there for a few minutes. There is good research to show that Ketoconazole is an effective anti-fungal.

So check it out: it’s not the Cleanest product in the world like I said. There are some gnarly Chemicals, but you take that little Exposure to that several days a week instead of being bald. Most People do make that trade all day long. So if you’re worried about your hairline and not taking Ketoconazole Shampoo, you’re missing out. This Can slow down the process and, again, if You let it sit in your hair, especially In those places where you’re going to Lose it right here in the front and in The back for about five minutes in the Shower a couple of days a week, and if Anything you’re slowing down that now. You can do a topical Anastrozole. There’s a topical. With a compounding pharmacist, you can get a higher dose of Ketoconazole. With a natural DHT blocker, Anastrozole is the aromatase Inhibitor. I’m drawing a blank on this, but I worked with doctor One.

From a compounding pharmacist, it was like a hundred dollars a month. I wanted to spend less. Still, if you have a strong familial link with male pattern baldness, that might be something to work with an integrative nurse practitioner or medical doctor with a compounding pharmacy. You can get a topical Propecia with a higher potency Ketoconazole in shampoo and rub that in your hair. That is more effective than taking an oral Propecia. We know that oral is the five Alpha reductase enzyme that converts testosterone to DHT can have irreversible effects, and that can lead to erectile dysfunction and problems sexually. You don’t want to take that orally even though you want to preserve your hairline. Topically may affect the hair follicle and help prevent DHT from causing baldness without all the negatives. Anyway, I wanted to share this with you.



The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel or website.

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